Research Scientist
Company: Odyssey Systems Consulting Group, Ltd.
Location: Biloxi
Posted on: August 2, 2022
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Job Description:
Position Summary
Odyssey Systems is recruiting for a Research Scientist to serve as
a Subject Matter Expert (SME) for the Clinical Research Laboratory
and as oversight for the research being conducted in support of the
81st Medical Group Graduate Health Education program and the
Clinical Research Laboratory research portfolio. The Research
Scientist will provide technical/scientific guidance and will
advise CRL director, GHSE director and 81 MDG leadership in regard
to strategic planning for current and future research projects.
He/she will ensure research projects align with Air Force Medical
Service (AFMS) and Defense Health Agency (DHA) strategic plans to
improve medical care of the warfighter and DoD beneficiary
population. He/she will work closely with a Molecular Biologist
Researcher and will conduct and oversee performance of complex
molecular assays, development, validation, quality control and
quality assurance activities of the Clinical Research
Laboratory.
Note: The RFP is expected to release in May with an expected start
date at the end of July 2022.
Responsibilities
Duties include, but not limited to:
Protocol Support: develop, write, execute (as required) and produce
publication in support of current and future grants and protocols
as required for CRL Core Scientific Projects, including Cancer
protocols in support of the DoD MURTHA collaboration, Air Force
Capability Gap research including swine models, Air Force Special
Operations Training and DaVinci Surgical Robotic training/surgery.
Work with clinicians on human studies when possible. Based on the
major challenges of current medicine, develop vision and mission
for solutions to improve the diagnosis, treatment, and outcome of
breast cancer, prostate cancer and other cancers. Develop long-term
objectives to identify targets for diagnosis and therapy of
cancers. Generate, evaluate, and select strategies to design
research proposals for target discovery. Implement strategies to
perform experiments. Assess and evaluate identifications for
potential clinical application. Validate discovered novel invention
and develop clinical trials. Plan, develop, and create cell and
animal models for medical research. Evaluate the risk factors.
Perform accuracy/efficiency data analysis. Design studies to
improve the diagnosis, treatment/prognosis of KMC subspecialty
supported chronic disease i.e. cancer, diabetes, En Route Care,
Wound Care, and other military related diseases. Develop contracts
and work with commercial vendors and the MURTHA Cancer center
sequencing center to obtain required services as required.
Collaborations: Collaborate with John P. Murtha Cancer Center
(MCC), WALTER REED NATIONAL MILITARY MEDICAL CENTER (WRNMMC)
(Bethesda, MD) on Tissue Biobank and Cancer research projects and
be a primary investigator if required. Obtain official DoD
Investigator status with MCC (as vetted by MCC), develop and
conduct breast, prostate and colorectal cancer with MCC WRNMMC. As
a regional CIP of MCC WRNMMC, collaborate MCC WRNMMC on cancer
tissue bank.
Participate as a member and scientific reviewer on the IRB and
IACUC committees. Work locally with in- person communications with
IRB and IACUC to support research, review medical research projects
in Keesler Medical Center. Assess the risks and benefits of various
medical procedures of designed study and protect patients; human
and animal) rights. Minimize the risk for patients while ensuring
reasonable designed study is successful. Evaluate proposed animal
research, assure study design is statistically and scientifically
sound. Ensure minimal patient usage and risk in the proposed
studies while still being able to reach reasonable scientific
conclusions. Utilize eIACUC and eIRB databases for entering,
editing and reviewing research protocols.
Work with Air Force Special Operations Command (AFSOC) to develop
Tactical Combat Casualty Care site at the Keesler CIF. Develop and
coordinate a memorandum of agreement (MOA) between interested
parties. Coordinate obtaining TCCC designation with AFSOC.
Coordinate development of R&D efforts (development of field
requirements & development of research based on training with AFSOC
based on training protocols and efforts.
Develop collaboration documents and technology transfer
documentation as required. Work with Air Force Technology Transfer
Office and AF Keesler CRL to effectively create agreements that
promote collaboration with internal (DoD) and external (Commercial
and University) partners. The incumbent will be solely responsible
for the development of CRADAs (Cooperative Research and Development
Agreements) as required. Development of patent licensing agreements
as required. Development of Test services agreements as required.
Creation of all other technology transfer agreements as
required.
Assist in Graduate Medical Education: Provides advanced education,
training, and support of military related medical research for
trainees and medical staff. Meets and discusses with trainees about
the military related medical research. Provides specific education
and training to develop medical research skills/accelerate their
career development and readiness. Teach trainees to find applicable
subjects and plan related projects specifically with the
application of technology transfer techniques. Guide trainees to
develop reasonable proposals in related medical fields. Support
trainees to conduct experiments to complete the proposed studies.
Supervise trainees to prepare reports, manuscripts, and
presentations. Onsite SME guidance, support and assistance for KMC
medical staff to plan, design, and develop medical research.
Publication Support: Oversee, assist and advise in the generation,
presentation, review and clearance of publications in support of
Keesler Medical Center.
Serve as subject matter expert on procedural, technical, and
scientific issues regarding molecular research and the most complex
molecular laboratory testing situations. Performs and oversees
performance of complex molecular diagnostic testing. Oversees assay
development and validation of all molecular tests in the
laboratory. Oversees all quality control and quality assurance
activities for the Molecular Laboratory. Provides
technical/scientific guidance and advises CRL Director, GHSE
Director and 81 MDG staff in regard to strategic planning for
current and future molecular assay testing, to include but not
limited to, polymerase chain reaction (PCR) testing, next
generation sequencing (NGS), Northern, Southern and Western blots,
"omics", to name a few. Provides
information/guidance/recommendations to CRL, GHSE and 81 MDG staff
on matters relative to test findings and on methods and
applications of molecular technologies. Ensures Molecular Lab
compliance with established accreditation standards as applicable.
Serves as an advisor to Department of Defense, Veterans Healthcare
Administration, and other federal agencies on utilization of new
molecular tests and provides written and verbal feedback to
critique new modalities applied, as required. Serves as consultant
to the CRL, GHSE program and 81 MDG leadership and staff on
molecular testing and performs ongoing evaluation/research on
molecular testing as it relates to on-going and future Clinical
Research portfolio. Develop cutting edge technologies to improve
the medical research in Keesler Medical Center. Develop and
implement state-of-the-art biomedical techniques for basic and
translational medical research. Apply laser microdissection
technologies to micro-isolate interested single cells or tissue
portions for detailed molecular and "omics" analysis (Genomics,
Transcriptomics, Proteomics, Lipidomics, Metabolomics), and couple
high and precise resolution of cellular and tissue imaging with
multiplex labeling to study cell-cell interaction, cell
phenotyping, and cell function. Develop Western blot PAGE and 2D
DIGE for protein quantitative measurements. Apply real-time PCR and
various genomic techniques for multiple gene expression analysis.
Develop multiplex cell phenotyping analysis using flow cytometry.
Establish 2D and 3D cell culture systems to develop in vitro cancer
and other disease models for cellular function analysis and
therapeutic studies. Develop xenograft human mouse cancer and other
disease models to test and validate experimental therapies.
Oversee and assist in maintaining and troubleshooting advanced
biomedical research equipment to support medical research in
Clinical Research Laboratory of Keesler Medical Center. Assure the
following equipment (not all inclusive) work and function properly:
Tri Gas CO2 Incubator, Class II type A2 Safety Cabinet, Inverted
microscope, BioLog LP System, xMark (ELISA), MAGPix (Cytokine),
QuantStudio 6 Flex (Real- time PCR), Attune NxT (Flow Cytometer),
Criterion Cell/Blotter PROTEANi12 IEF system (western blot and 2D
DIGE), Molecular Imaging (western blot and 3D DIGE Imaging), Leica
Biosystems (ASP3030- tissue processor, CM3050S-Cryostate,
VT1200VT-Microtome, CV5030-Glass Coverslipper, BANDRX-Multiplex
stainer) (tissue processing, multiplex staining), Zeiss LSM 880
(supper resolution confocal microscopy system), Zeiss PALM (laser
dissection system). Possess the ability to conceive, synthesize and
develop training, GME, and R&D protocol research utilizing
these techniques.
Training: Coordinates and/or conducts molecular laboratory
education and training for new staff and ensures competency and
proficiency maintenance of molecular laboratory techniques of the
molecular laboratory staff. Oversees, conducts, and/or coordinates
molecular procedures, theory and equipment operation training for
residents, medical students and other GHSE students that are
participating in molecular research. Develops and oversees
educational and academic affiliations with other institutions in
the area of molecular research, exchanges information with other
medical and academic centers and molecular scientists, participates
in studies as directed, and attends conferences and lectures
pertaining to the field of molecular biology and clinical research.
Ensures all department certification and continuing education
requirements are met. Prepares for and presents clinical molecular
research topics and case studies internally and externally as
needed.
Qualifications
MD or Ph.D. in Microbiology, Immunology, Physiology, Molecular
Biology, Biochemistry or another related scientific field
5 to 10 years post-doctoral experience
Preferred Qualifications:
Experience supporting cancer clinical trials
Prior experience with a military medical agency
Additional Information:
Work is on-site at the Keesler Medical Center in Biloxi, MS
US Citizenship required
#LI-KC1Company Overview
Odyssey Systems Consulting Group, is an innovative small business
committed to providing world-class technical, management, and
training support services to government and public sector clients.
We focus on people, processes, and performance to deliver superior
results. Since our inception in 1997, our commitment to mission
success and customer satisfaction has been recognized with
exponential growth and exceptional past performance ratings. We
accept challenging assignments and drive projects from the planning
stages, through implementation, and into operations and
support.
Please note: Final compensation for this position will be
determined by various factors such as the Federal Government
contract labor categories and contract wage rates, relevant work
experience, specific skills and competencies, geographic location,
education, and certifications.
Equal Opportunity Employer/Protected Veterans/Individuals with
Disabilities
Keywords: Odyssey Systems Consulting Group, Ltd., Biloxi , Research Scientist, Other , Biloxi, Mississippi
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